النتائج (
الإنجليزية) 2:
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Public health burden of large prostate cancer. And it is expected to total 220 800 new cases of prostate cancer and 27 540 deaths from this disease in the United States by 2015, making it the most common among males in the United States Nondermatulogik cancer. A man in danger of prostate cancer is one out of every seven. Prostate cancer is the second leading cause of cancer death in men, exceeded only lung cancer.
Remaining symptoms of some men with prostate cancer die from causes unrelated and not as a result of the cancer itself. This may be due to the advanced age of many of the men at the time of diagnosis, and slow tumor growth, or response to treatment. Estimated number of men with prostate cancer underlying (ie prostate which is present in the prostate gland cancer but never detected or diagnosed during the patient's life) is greater than the number of men who have the disease detected clinically. It is necessary to understand the biological and genetic mechanisms that determine why some prostate cancers remain clinically silent, while others cause serious diseases and even life-threatening.
Prostate cancer and exhibits enormous differences in the incidence among the population in all parts of the world; the proportion of countries with high and low cancer rates Prostate ranges observed for 100-fold. Asians usually have a very low ratio of men from prostate cancer, with incidence rates adjusted by age, ranging from 2 to 10 cases per 100,000 men. It observed the highest rates generally in northern European countries. However, American men of African descent, the highest incidence of prostate cancer in the world; in the United States, American men of African descent have a higher rate of 60% of white men occurs. American men of African descent reported to be almost double the death rate - especially prostate cancer compared with white men of non-Hispanics. May narrow the differences in survival for prostate cancer race with time estimates.
This may be differences as a result of the interaction between genetic and environmental and social impacts (such as access to health care), which may affect the development and progression of the disease. Differences in screening practices also had a significant effect on the incidence of prostate cancer, prostate cancer diagnosis by allowing some patients before symptoms develop or before abnormalities on physical examination are discovered. It was suggested that an analysis based on data from Sweden to the population that the diagnosis of prostate cancer in one brother lead to early diagnosis in the second brother screening using prostate-specific antigen (PSA). This may represent an increase in prostate cancer in younger men diagnosed it was not clear in the incidence of data at the national level. Genetic contribution to the risk of prostate cancer has been documented, which is to increase knowledge with the knowledge of the molecular genetics of the disease, and despite the fact that a lot of what is known is not clinically after implementation. Transformation of prostate epithelial malignant cells and the development of prostate cancer are likely to result from a complex series of initiation and promotional events under genetic and environmental influences on both.
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